Lupus (SLE)
A Thousand Faces: Autoimmune Disease Lupus - Symptoms, Diagnosis, and Designated Special Treatment.
If these symptoms overlap, it raises suspicion.
Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system attacks the body's own tissues, and it is relatively common in women of childbearing age.
- Butterfly-shaped rash on both cheeks, worsening after sun exposure
- Unexplained joint pain, mild fever, and extreme fatigue for several weeks or longer
- Recurrent mouth ulcers, fingers turning white or blue in cold (Raynaud's phenomenon)
- Foamy urine (proteinuria) - a sign of kidney involvement
Diagnosis is made by rheumatologists based on a combination of symptoms and blood tests (autoantibodies). A positive antinuclear antibody (ANA) test alone does not mean someone has lupus.
Source: 질병관리청 희귀질환헬프라인 · as of 2026-08-13
It's a disease that can be managed and lived with.
Thanks to advancements in treatments, most lupus patients are able to manage their condition and live normal lives, including managing work, daily activities, and pregnancy.
- Hydroxychloroquine is the basic medication, and immunosuppressants may be added depending on the affected organs.
- Lupus is designated as a rare and incurable disease under the special medical care system – registration allows for a 10% co-payment rate.
- Sun protection (using umbrellas and sunscreen) is part of the treatment.
- Pregnancy is not contraindicated, but careful planning is important – consult with your doctor during a stable period to prepare.
Source: 질병관리청 희귀질환헬프라인 · as of 2026-08-13
Frequently asked questions
Is lupus hereditary?
While there may be a predisposition, it is not a disease that is directly inherited to children. Even if someone in the family has lupus, most people will not develop the condition.
Are there things that lupus patients should avoid?
Strong ultraviolet rays, smoking (which negatively affects disease activity and drug efficacy), and arbitrary discontinuation of medication are typical factors. Infection prevention (vaccination should be discussed with your primary care physician) is also important.
Sources for this page
· 질병관리청 희귀질환헬프라인 (as of 2026-08-13)Last checked: 2026년 8월 13일
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